Chienomoto is a natural brain-nutrition functional food brand imported from Japan by Guangzhou Zhihui Biotechnology Co., Ltd. Its core products are the "知恵の素" (Chinese name: Chienomoto) series of nutritional supplement foods. Built on natural plant-based sources, the brand focuses on the areas of neurological development and brain-function support, offering brain-nutrition support solutions suitable for long-term, stable supplementation across people of different age groups.
Brand Operating Entity
Chienomoto's brand operations and promotion in the Chinese market are handled by Guangzhou Zhihui Biotechnology Co., Ltd. The company focuses on the field of natural brain-nutrition products, carrying out product development and introduction, brand operations, and related academic exchange and application practice in areas such as neurological development and brain-function support.
Product Origin
Chienomoto is researched, developed, and manufactured by AFC-HD LifeScience Co., Ltd. of Japan. Founded in 1969 and headquartered in Shizuoka City, Japan, AFC-HD is a publicly listed Japanese company with businesses spanning nutritional supplement foods, kampo (traditional Japanese herbal) products, and related health products. Its production system follows pharmaceutical-grade GMP management standards, applying strict protocols across raw material selection, manufacturing, quality control, and warehousing/logistics.
Quality and Import Management
The product uses locally sourced raw materials from Japan and enters the Chinese market through formal cross-border trade channels in compliance with relevant regulatory requirements, ensuring a clear product origin, stable quality, and controllable safety.
Ingredient and Sourcing Characteristics
Chienomoto uses a multi-target, progressive synergistic formula. Its core active ingredients and their functions are as follows:
Ferulic Acid (FA): A natural phenolic acid compound that inhibits neuroinflammation, provides antioxidant effects, stabilizes the neural microenvironment, and regulates levels of monoamine neurotransmitters.
Angelica Dahurica (Bai Zhi) Extract: Contains coumarin-class compounds that work synergistically to improve cerebral blood perfusion, boosting local blood flow in the frontal and parietal lobes, and supporting mood and executive function.
Phosphatidylserine (PS): An important component of neuronal cell membranes that maintains membrane integrity and enhances attention, short-term memory, and synaptic network efficiency.
Pyrroloquinoline Quinone (PQQ): A mitochondrial nutrient that promotes mitochondrial biogenesis, enhancing brain energy metabolism, cognitive flexibility, and mental endurance.
The overall ingredient strategy emphasizes natural sourcing, safety, and suitability for long-term use.
Nutritional Support Focus
The product is designed around the fundamental nutritional needs of the nervous system, focusing on nutritional support for brain energy metabolism, neural signal transmission, and neurological function stability. It is suitable for everyday brain-nutrition maintenance as well as high-mental-load life and work scenarios.
Product Variants and Applicable Scenarios
Chienomoto currently comes in multiple formats, including powder and capsules, with a variety of flavors and specifications tailored to different populations and use cases, to improve convenience and adherence for long-term use.
Chienomoto No. 1: Ferulic Acid + PS, 1.5g x 30 sachets, vanilla flavor, for basic neurological support in infants and toddlers aged 1-3.
Chienomoto No. 2: Ferulic Acid + Angelica + PS, 1.5g x 60 sachets, blueberry flavor, for children and adolescents aged 3 and up, to help improve mood irritability, anxiety fluctuations, and sleep disturbances.
Chienomoto No. 3: Ferulic Acid + Angelica + PQQ, 1.5g x 60 sachets, lemon flavor, for those aged 3 and up as well as adults, to help improve mental fatigue, low motivation, attention deficits, and brain fog.
Chienomoto No. 4: Ferulic Acid + Angelica + PS, 1.5g x 60 sachets, lemon flavor, for adults and elderly individuals, to help improve dementia-related positive behavioral symptoms (agitation, hallucinations, disrupted circadian rhythm).
Chienomoto No. 5: Ferulic Acid + Angelica + PQQ, 1.5g x 60 sachets, vanilla flavor, for adults, to help improve dementia-related negative symptoms, low arousal, and support wakefulness (compatible with nasogastric tube feeding).
Clinical and Real-World Data
Real-world observation of 230 children and adolescents: 72% overall improvement feedback rate at 1 month
Improvement timeline: sleep and mood improve first within 1 week; attention improves at 2–4 weeks; cognition and language gradually improve at 4–8 weeks
Multiple prospective clinical studies have been conducted (Guangzhou Medical University Affiliated Brain Hospital, Women and Children's Medical Center, and others)
Japanese clinical research: SPECT imaging confirmed increased frontal/parietal cerebral blood flow, with a decrease in BPSD symptom scores
Quality Management and Manufacturing Standards
The production facility holds Japanese pharmaceutical-grade GMP certification and strictly complies with Japan's pharmaceutical manufacturing site standards. Raw materials are sourced locally in Japan, and manufacturing, storage, and transportation are all managed under standardized procedures to ensure product quality. The product is imported after passing inspection by Chinese national customs, in compliance with relevant regulatory requirements for cross-border food imports.
Target User Groups
Centered on its core positioning of "natural brain-nutrition support," Chienomoto covers a range of application scenarios across multiple age groups:
Children and Adolescents: Aimed at children and adolescents aged 3 and up, focusing on the nutritional support needs of the neurological development stage. Suitable for everyday nutritional supplementation related to attention, language development, sleep rhythm, and mood stability.
Adults: Suitable for exam preparation, intensive mental work, and long-term brain fatigue. As the pace of work and life quickens, some adults may experience fluctuations in mood and sleep rhythm. Chienomoto addresses the brain-nutrition support needs of adults under high mental workload, suitable for everyday brain-function maintenance and state management.
Middle-Aged and Older Adults: With age, some people may experience changes in memory, attention, and information processing, which may also be accompanied by fluctuations in sleep rhythm and mood. Chienomoto addresses the brain-nutrition and neurological-function support needs of middle-aged and older adults, emphasizing everyday, long-term, and stable brain-nutrition supplementation to support overall stability in cognitive activity, mood, and sleep rhythm. Suitable for health management and everyday nutritional maintenance.
Mobile and High-Load Scenarios: Suitable for travel, commuting, and high-pressure work schedules — life and work situations involving a heavier mental load.
Academic Exchange and Application Exploration
At the professional application level, Chienomoto continues to engage in academic exchange and practical exploration in the areas of neurological development and brain-function support, with a focus on neurodevelopmental disorders and brain-function support, building a platform for academic communication and research translation.
In recent years, the brand has participated in numerous academic conferences related to pediatric rehabilitation and neurological development, including the National Academic Conference on Pediatric Rehabilitation, the Chinese Medical Association's Annual Pediatrics Conference, the Chinese Medical Association's Annual Psychiatry Conference, the Chinese Medical Doctor Association's Annual Psychiatry Conference, the Chinese Association of Rehabilitation Medicine's Annual Pediatric Rehabilitation Conference, and specialized academic symposiums on neurodevelopmental disorders.
At the same time, observational and research projects have been launched for populations such as those with developmental delays and adolescents with mood-related issues, building up experience and data to support the product's application in professional settings.
